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Biblioteca (s) : |
INIA Tacuarembó. |
Fecha : |
29/10/2014 |
Actualizado : |
08/10/2019 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Autor : |
CAZZULI, F.; LAGOMARSINO, X.; LUZARDO, S.; MONTOSSI, F. |
Afiliación : |
FIORELLA CARLA CAZZULI ALBA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; XIMENA MARIA LAGOMARSINO LARRIERA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; SANTIAGO FELIPE LUZARDO VILLAR, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; FABIO MARCELO MONTOSSI PORCHILE, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
Título : |
¿Existe respuesta a la suplementación estratégica en novillos de recría pastoreando sudangrás y sorgo forrajero? // Is there a response to strategic supplementation of yearling steers grazing sudangrass and forage sorghum? |
Fecha de publicación : |
2019 |
Fuente / Imprenta : |
Agro Sur, 2019, v. 47no. 2, p. 7-17. |
Idioma : |
Español |
Notas : |
Article history: Received: 09.05.2019 // Accepted: 18.07.2019. |
Contenido : |
Within the context of sustainable intensification of extensive livestock production systems, the inclusion of reduced areas of high productivity combined with strategic supplementation would allow an animal production increase. Sudangrass and direct grazing sorghum appear as alternatives because of their agroecological adaptation and high forage production. To evaluate the effect of these forage basis combined with the use of protein supplementation on average daily gain (ADG) and live weight (LW), 40 Hereford yearling steers (LW, Year 1 = 287 ± 35 kg; Year 2 = 271 ± 19 kg) were used in a random 2 x 2 factorial design for two years, where forage basis (sudangrass ? Sd ? or BMR sorghum ? Sg) and supplementation (0.8% LW with sunflower expeller: with ? S ? or without ? NOS) were evaluated. The animals were randomly allocated to 4 treatments with two replicates: SdNOS, SdS, SgNOS, and SgS. Average daily gain was significantly affected by forage basis and supplementation (Sd = 0.833 vs. Sg = 0.899 kg animal-1 d-1, P < 0.05; NOS = 0.739 kg animal-1 d-1 vs. S = 0.992 kg animal-1 d-1, P < 0.01), as was final LW (Sd = 342.3 vs. Sd = 347.1 kg, P < 0.05; NOS = 334.7 kg vs. S =354.7 kg; P < 0.01). The use of forage sorghums combined with strategic supplementation improved the rearing of steers during summer // RESUMEN: En el marco de una intensificación sostenible de la ganadería extensiva, la inclusión de áreas reducidas de alta productividad combinada con suplementación estratégica permitiría mejorar la productividad animal. El uso de sudangrás o sorgo forrajero es una alternativa dada su mejor adaptación agroecológica a suelos más marginales y alta producción forrajera. Con el objetivo de evaluar el efecto de estas dos bases forrajeras combinadas con suplementación proteica sobre la ganancia media diaria (GMD) y el peso vivo (PV), por dos años, 40 novillos Hereford de sobreaño (PV, Año 1 = 287 ± 35 kg; Año 2 = 271 ± 19 kg) fueron utilizados en un diseño de parcelas al azar con un arreglo factorial de 2 x 2, en donde se evaluó la base forrajera (sudangrás ? Sd ? o sorgo forrajero BMR ? Sg) y la suplementación (0,8% del PV con expeller de girasol: con ?CS? o sin ?SS). Los novillos fueron asignados al azar a 4 tratamientos con dos repeticiones cada uno: SdSS, SdCS, SgSS y SgCS. La GMD fue afectada significativamente por la base forrajera y suplementación (Sd = 0,833 vs. Sg = 0,899 kg animal-1 d-1, P < 0,05; SS = 0,739 kg animal-1 d-1, CS = 0,992 kg animal-1 d -1, P < 0,01), así como el PV final (Sd = 342,3 vs. Sd = 347,1 kg, P < 0,05; SS = 334,7 kg, CS =354,7 kg, P < 0,01). El uso de sorgos forrajeros con suplementación estratégica mejoró la recría estival de novillos. MenosWithin the context of sustainable intensification of extensive livestock production systems, the inclusion of reduced areas of high productivity combined with strategic supplementation would allow an animal production increase. Sudangrass and direct grazing sorghum appear as alternatives because of their agroecological adaptation and high forage production. To evaluate the effect of these forage basis combined with the use of protein supplementation on average daily gain (ADG) and live weight (LW), 40 Hereford yearling steers (LW, Year 1 = 287 ± 35 kg; Year 2 = 271 ± 19 kg) were used in a random 2 x 2 factorial design for two years, where forage basis (sudangrass ? Sd ? or BMR sorghum ? Sg) and supplementation (0.8% LW with sunflower expeller: with ? S ? or without ? NOS) were evaluated. The animals were randomly allocated to 4 treatments with two replicates: SdNOS, SdS, SgNOS, and SgS. Average daily gain was significantly affected by forage basis and supplementation (Sd = 0.833 vs. Sg = 0.899 kg animal-1 d-1, P < 0.05; NOS = 0.739 kg animal-1 d-1 vs. S = 0.992 kg animal-1 d-1, P < 0.01), as was final LW (Sd = 342.3 vs. Sd = 347.1 kg, P < 0.05; NOS = 334.7 kg vs. S =354.7 kg; P < 0.01). The use of forage sorghums combined with strategic supplementation improved the rearing of steers during summer // RESUMEN: En el marco de una intensificación sostenible de la ganadería extensiva, la inclusión de áreas reducidas de alta productividad combinada con suplementación estratégica p... Presentar Todo |
Palabras claves : |
BMR SORGHUM FORAGE CROP; EXPELLER DE GIRASOL; NOVILLOS; SORGO FORRAJERO BMR; STEERS; SUDANGRÁS; SUDANGRASS FORAGE CROP; SUNFLOWER EXPELLER; SUPLEMENTACIÓN; SUPPLEMENTATION. |
Thesagro : |
PRODUCCIÓN ANIMAL. |
Asunto categoría : |
L01 Ganadería |
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/13455/1/Cazzuli-2019.pdf
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Marc : |
LEADER 03758nam a2200289 a 4500 001 1051365 005 2019-10-08 008 2019 bl uuuu u00u1 u #d 100 1 $aCAZZULI, F. 245 $a¿Existe respuesta a la suplementación estratégica en novillos de recría pastoreando sudangrás y sorgo forrajero? // Is there a response to strategic supplementation of yearling steers grazing sudangrass and forage sorghum?$h[electronic resource] 260 $aAgro Sur, 2019, v. 47no. 2, p. 7-17.$c2019 500 $aArticle history: Received: 09.05.2019 // Accepted: 18.07.2019. 520 $aWithin the context of sustainable intensification of extensive livestock production systems, the inclusion of reduced areas of high productivity combined with strategic supplementation would allow an animal production increase. Sudangrass and direct grazing sorghum appear as alternatives because of their agroecological adaptation and high forage production. To evaluate the effect of these forage basis combined with the use of protein supplementation on average daily gain (ADG) and live weight (LW), 40 Hereford yearling steers (LW, Year 1 = 287 ± 35 kg; Year 2 = 271 ± 19 kg) were used in a random 2 x 2 factorial design for two years, where forage basis (sudangrass ? Sd ? or BMR sorghum ? Sg) and supplementation (0.8% LW with sunflower expeller: with ? S ? or without ? NOS) were evaluated. The animals were randomly allocated to 4 treatments with two replicates: SdNOS, SdS, SgNOS, and SgS. Average daily gain was significantly affected by forage basis and supplementation (Sd = 0.833 vs. Sg = 0.899 kg animal-1 d-1, P < 0.05; NOS = 0.739 kg animal-1 d-1 vs. S = 0.992 kg animal-1 d-1, P < 0.01), as was final LW (Sd = 342.3 vs. Sd = 347.1 kg, P < 0.05; NOS = 334.7 kg vs. S =354.7 kg; P < 0.01). The use of forage sorghums combined with strategic supplementation improved the rearing of steers during summer // RESUMEN: En el marco de una intensificación sostenible de la ganadería extensiva, la inclusión de áreas reducidas de alta productividad combinada con suplementación estratégica permitiría mejorar la productividad animal. El uso de sudangrás o sorgo forrajero es una alternativa dada su mejor adaptación agroecológica a suelos más marginales y alta producción forrajera. Con el objetivo de evaluar el efecto de estas dos bases forrajeras combinadas con suplementación proteica sobre la ganancia media diaria (GMD) y el peso vivo (PV), por dos años, 40 novillos Hereford de sobreaño (PV, Año 1 = 287 ± 35 kg; Año 2 = 271 ± 19 kg) fueron utilizados en un diseño de parcelas al azar con un arreglo factorial de 2 x 2, en donde se evaluó la base forrajera (sudangrás ? Sd ? o sorgo forrajero BMR ? Sg) y la suplementación (0,8% del PV con expeller de girasol: con ?CS? o sin ?SS). Los novillos fueron asignados al azar a 4 tratamientos con dos repeticiones cada uno: SdSS, SdCS, SgSS y SgCS. La GMD fue afectada significativamente por la base forrajera y suplementación (Sd = 0,833 vs. Sg = 0,899 kg animal-1 d-1, P < 0,05; SS = 0,739 kg animal-1 d-1, CS = 0,992 kg animal-1 d -1, P < 0,01), así como el PV final (Sd = 342,3 vs. Sd = 347,1 kg, P < 0,05; SS = 334,7 kg, CS =354,7 kg, P < 0,01). El uso de sorgos forrajeros con suplementación estratégica mejoró la recría estival de novillos. 650 $aPRODUCCIÓN ANIMAL 653 $aBMR SORGHUM FORAGE CROP 653 $aEXPELLER DE GIRASOL 653 $aNOVILLOS 653 $aSORGO FORRAJERO BMR 653 $aSTEERS 653 $aSUDANGRÁS 653 $aSUDANGRASS FORAGE CROP 653 $aSUNFLOWER EXPELLER 653 $aSUPLEMENTACIÓN 653 $aSUPPLEMENTATION 700 1 $aLAGOMARSINO, X. 700 1 $aLUZARDO, S. 700 1 $aMONTOSSI, F.
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Registro original : |
INIA Tacuarembó (TBO) |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
Fecha actual : |
17/04/2024 |
Actualizado : |
17/04/2024 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Circulación / Nivel : |
Internacional - -- |
Autor : |
AREVALO, A.P.; BASIKA, T.; ANCHETA, S.; PERELMUTER, K.; RICCIARDI, A.; BOLLATI-FOGOLÍN, M.; CRISPO, M. |
Afiliación : |
ANA PAULA AREVALO, Institut Pasteur de Montevideo, Laboratory Animals Biotechnology Unit, Montevideo, Uruguay; TATIANA BASIKA, Unidad Mixta entre Instituto Pasteur de Montevideo e INIA (UMPI), Montevideo, Uruguay; Institut Pasteur de Montevideo, Laboratory Animals Biotechnology Unit, Montevideo, Uruguay; Institut Pasteur de Montevideo, Cell Biology Unit, Montevideo, Uruguay; SERGIO ANCHETA, Institut Pasteur de Montevideo, Laboratory Animals Biotechnology Unit, Montevideo, Uruguay; KAREN PERELMUTER, Institut Pasteur de Montevideo, Cell Biology Unit, Montevideo, Uruguay; ALEJANDRO RICCIARDI; MARIELA BOLLATI-FOGOLÍN, Institut Pasteur de Montevideo, Cell Biology Unit, Montevideo, Uruguay; MARTINA CRISPO, Institut Pasteur de Montevideo, Laboratory Animals Biotechnology Unit, Montevideo, Uruguay. |
Título : |
3R's applied to in vivo biological activity of recombinant human erythropoietin assay. |
Complemento del título : |
Technical Article. |
Fecha de publicación : |
2023 |
Fuente / Imprenta : |
Biological Models Research and Technology Journal. 2023, Volume 3, Issue 1, e00012023. http://dx.doi.org/10.4322/2675-9225.00012023 -- OPEN ACCESS. |
ISSN : |
2675-9225 |
DOI : |
10.4322/2675-9225.00012023 |
Idioma : |
Inglés |
Notas : |
Article history: Submitted date 9 February 2023, Accepted date 19 April 2023. -- Correspondence: Crispo, M.; Institut Pasteur de Montevideo, Laboratory Animals Biotechnology Unit, Montevideo, Uruguay; email:crispo@pasteur.edu.uy -- FUNDING: This work was supported by FOCEM (MERCOSUR Structural Convergence Fund), COF 03/11 and ANII (EQL_2013_X_1_2). -- Document type: Article Bronze Open Access. --
Publisher: Brazilian Society for Laboratory Animal Science. |
Contenido : |
ABSTRACT.- An enhanced protocol for the evaluation of in vivo biological activity of recombinant human erythropoietin (rhEPO) assay in mice is described, following European Pharmacopoeia (Ph. Eur.) version 10.0 guideline and optimized by applying the principles of Replacement, Reduction and Refinement (3Rs) in animal experimentation. In Laboratory Animal Science, one of the main principles is to optimize the experimental protocols in order to achieve the best results with the lowest number of animals and refine the procedures to avoid unnecessary suffering. The main objective of this protocol is to comply with international guidelines for rhEPO evaluation, applying refinement on procedures and reduction in animal use. Some of the features included in this protocol are the increase in number of rhEPO batches tested simultaneously against an international standard, leading to a substantial reduction in the number of animal's used, and refinement on animal handling techniques for subcutaneous drug administration and blood withdrawal. The implemented improvements were validated by reticulocyte estimation to ensure compliance with international criteria established for this trial and institutional quality management system. © 2023, Brazilian Society for Laboratory Animal Science. All rights reserved. |
Palabras claves : |
3R’s; Biological activity; Erythropoietin; European Pharmacopeia; Mice; UNIDAD MIXTA PASTEUR + INIA. |
Asunto categoría : |
A50 Investigación agraria |
URL : |
https://bmrtsbcaljournal.com/article/10.4322/2675-9225.00012023/pdf/bmrt-3-1-e00012023.pdf
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Marc : |
LEADER 02721naa a2200301 a 4500 001 1064596 005 2024-04-17 008 2023 bl uuuu u00u1 u #d 022 $a2675-9225 024 7 $a10.4322/2675-9225.00012023$2DOI 100 1 $aAREVALO, A.P. 245 $a3R's applied to in vivo biological activity of recombinant human erythropoietin assay.$h[electronic resource] 260 $c2023 500 $aArticle history: Submitted date 9 February 2023, Accepted date 19 April 2023. -- Correspondence: Crispo, M.; Institut Pasteur de Montevideo, Laboratory Animals Biotechnology Unit, Montevideo, Uruguay; email:crispo@pasteur.edu.uy -- FUNDING: This work was supported by FOCEM (MERCOSUR Structural Convergence Fund), COF 03/11 and ANII (EQL_2013_X_1_2). -- Document type: Article Bronze Open Access. -- Publisher: Brazilian Society for Laboratory Animal Science. 520 $aABSTRACT.- An enhanced protocol for the evaluation of in vivo biological activity of recombinant human erythropoietin (rhEPO) assay in mice is described, following European Pharmacopoeia (Ph. Eur.) version 10.0 guideline and optimized by applying the principles of Replacement, Reduction and Refinement (3Rs) in animal experimentation. In Laboratory Animal Science, one of the main principles is to optimize the experimental protocols in order to achieve the best results with the lowest number of animals and refine the procedures to avoid unnecessary suffering. The main objective of this protocol is to comply with international guidelines for rhEPO evaluation, applying refinement on procedures and reduction in animal use. Some of the features included in this protocol are the increase in number of rhEPO batches tested simultaneously against an international standard, leading to a substantial reduction in the number of animal's used, and refinement on animal handling techniques for subcutaneous drug administration and blood withdrawal. The implemented improvements were validated by reticulocyte estimation to ensure compliance with international criteria established for this trial and institutional quality management system. © 2023, Brazilian Society for Laboratory Animal Science. All rights reserved. 653 $a3R’s 653 $aBiological activity 653 $aErythropoietin 653 $aEuropean Pharmacopeia 653 $aMice 653 $aUNIDAD MIXTA PASTEUR + INIA 700 1 $aBASIKA, T. 700 1 $aANCHETA, S. 700 1 $aPERELMUTER, K. 700 1 $aRICCIARDI, A. 700 1 $aBOLLATI-FOGOLÍN, M. 700 1 $aCRISPO, M. 773 $tBiological Models Research and Technology Journal. 2023, Volume 3, Issue 1, e00012023. http://dx.doi.org/10.4322/2675-9225.00012023 -- OPEN ACCESS.
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